Published in Drug Week, June 25th, 2010
"We have developed a C-fluoropropyl analog of nisoxetine: ®-N-methyl-3-(3'-[F-18]fluoropropyl)phenoxy)-3-phenylpropanamine (F-18-MFP3) as a new potential PET radiotracer for NET with the advantage of the longer half-life of fluorine-18 (110 mm compared with carbon-11 (20 min). Synthesis of ®-N-methyl-3-(3'-fluoropropyl)phenoxy)-3-phenylpropanamine (MFP3) was achieved in five steps starting from...
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