Clinical Trial Research

Study results from M.S. Simberkoff and colleagues update understanding of clinical trial research

Published in Drug Week, July 2nd, 2010

"The herpes zoster vaccine is effective in preventing herpes zoster and postherpetic neuralgia in immunocompetent older adults. However, its safety has not been described in depth," scientists in the United States report.

"To describe local adverse effects and short-and long-term safety profiles of herpes zoster vaccine in immunocompetent older adults. Randomized, placebo-controlled trial with enrollment from November 1998 to September 2001 and follow-up through April 2004 (mean, 3.4 years). A Veterans Affairs Coordinating Center generated the permutated block randomization scheme, which was stratified by site and age. and follow-up study personnel were blinded to...

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Source: Drug Week (2010-07-02)

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