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Drug Research

New drug research study findings have been reported from University of Wisconsin, Department of Biochemistry

Published in Drug Week, July 9th, 2010

Researchers detail in 'Fluorescence-based technique for analyzing retinoic acid,' new data in drug research. "Retinoic acid (RA) is a potent transcriptional activator whose actions are mediated by members of the nuclear hormone receptor family. In addition to playing key roles in embryonic development and in tissue maintenance in the adult, RA is a potent anticarcinogenic agent currently in clinical use for treatment of various cancers," scientists in the United States report.

"Here, we describe an optical method for measuring the concentrations of RA in biological samples. This method uses cellular retinoic acid-binding protein I (CRABP-I), a protein that binds RA with...

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