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Pharmaceutical Research

Research on pharmaceutical research discussed by scientists at Okayama University

Published in Drug Week, October 15th, 2010

A report, 'Water sorption, glass transition, and protein-stabilizing behavior of an amorphous sucrose matrix combined with various materials,' is newly published data in Journal of Pharmaceutical Sciences. According to a study from Okayama, Japan, "The effects of various additives on the physical properties of an amorphous sugar matrix were compared. Amorphous, sugar-additive mixtures were prepared by freeze-drying and then rehumidified at given RHs."

"Sucrose and eighteen types of substances were used as the sugar and the additive, respectively, and water sorption, glass-to-rubber transition, and protein stabilization during freeze-drying for the various...

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