Cardiology
New cardiology study findings recently were reported by researchers at University of Michigan, Department of Internal Medicine
Published in Drug Week, October 22nd, 2010
Current study results from the report, 'Design and characterization of the first peptidomimetic molecule that prevents acidification-induced closure of cardiac gap junctions,' have been published. According to recent research from the United States, "Gap junctions are potential targets for pharmacologic intervention. We previously developed a series of peptide sequences that prevent closure of connexin43 (Cx43) channels, bind to cardiac Cx43, and prevent acidification-induced uncoupling of cardiac gap junctions."
"The purpose of this study was to identify and validate the minimum core active structure in peptides containing an RR-N/Q-Y motif. Based on that information,...
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Source: Drug Week (2010-10-22)
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