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Glioblastomas

Studies from San Raffaele Scientific Institute provide new data on glioblastomas

Published in Drug Week, October 29th, 2010

Data detailed in 'Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis' have been presented. According to recent research from Milan, Italy, "Epidermal growth factor receptor (EGFR) is a known diagnostic and, although controversial, prognostic marker of human glioblastoma multiforme (GBM). However, its functional role and biological significance in GBM remain elusive."

"Here, we show that multiple GBM cell subpopulations could be purified from the specimens of patients with GBM and from cancer stem cell (CSC) lines based on the expression of...

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