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Shire Acquires 99.21% of the Shares of Movetis N.V. and Announces Commencement of Squeeze-Out Tender Period

Published in Drug Week, October 29th, 2010

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty

biopharmaceutical company, announces that its wholly owned subsidiary Shire Holdings Luxembourg S.a.r.l. acquired 99.21% of the shares of Movetis NV on October 12, 2010, following a successful tender offer launched in September 2010.

As previously announced, Shire will proceed with a squeeze-out of those shares and warrants not tendered to the offer in accordance with applicable Belgian legislation. In this regard, an additional tender offer period opened, on the same terms, on October 12, 2010 and will close on November 2, 2010 at 4 pm CET.

Shares tendered into the...

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