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Genetics and Gastric Cancer

New research on genetics and gastric cancer from General Hospital summarized

Published in Drug Week, October 29th, 2010

Scientists discuss in 'Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer' new findings in genetics and gastric cancer. According to a study from Cuneo, Italy, "Current palliative chemotherapy (CT) regimens achieve clinical benefits in less than 50% of patients treated for metastatic gastric cancers, and long-term survivals are anecdotical. Genetic polymorphisms and differences at the level of transcription in genes involved in biological processes of drug metabolism, DNA repair and drug resistance can explain the observed individual differences in response to drugs, in survival and in different susceptibility to the toxic effects of CT."

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