Kidney Transplants
Data from INSERM provide new insights into kidney transplants
Published in Drug Week, December 3rd, 2010
2010 DEC 3 -- "The objective was to develop a population pharmacokinetic-pharmacogenetic model of mycophenolic acid following administration of mycophenolate mofetil (MMF) in de novo pediatric renal-transplant patients and identify factors that explain variability. The pharmacokinetic samples were collected from 89 de novo pediatric renal-transplant patients treated with MMF and studied during the first 60 postoperative days," scientists in Paris, France report.
"All patients were genotyped for UGT1A8-A9, UGT2B7, and ABCC2. pharmacokinetic analysis was performed with the NONMEM and was validated using bootstrap visual predictive check. The pharmacokinetic...
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Source: Drug Week (2010-12-03)
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