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Cancer Gene Therapy

New findings from University of Wurzburg describe advances in cancer gene therapy

Published in Drug Week, December 10th, 2010

2010 DEC 10 -- "Cancer arises from normal cells through the stepwise accumulation of genetic alterations. Cancer development can be studied by direct genetic manipulation within experimental models of tumorigenesis," scientists in Wurzburg, Germany report.

"Thereby, confusion by the genetic heterogeneity of patients can be circumvented. Moreover, identification of the critical changes that convert a pre-malignant cell into a metastatic, therapy resistant tumor cell, however, is one necessary step to develop effective and selective anti-cancer drugs. Thus, for the current study a cell culture model for malignant transformation was used: Primary human...

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