Ubiquitins
Findings from University of Wisconsin in Ubiquitins Reported
Published in Drug Week, January 21st, 2011
2011 JAN 21 -- Research findings, 'Protein aggregation in neurons following OGD: a role for Na+ and Ca2+ ionic dysregulation,' are discussed in a new report. According to a study from the United States, "In this study, we investigated whether disruption of Na(+) and Ca(2+) homeostasis via activation of Na(+)-K(+)-Cl(-) cotransporter isoform 1 (NKCC1) and reversal of Na(+)/Ca(2+) exchange (NCX(rev)) affects protein aggregation and degradation following oxygen-glucose deprivation (OGD). Cultured cortical neurons were subjected to 2 h OGD and 1-24 h reoxygenation (REOX)."
"Redistribution of ubiquitin and formation of ubiquitin-conjugated protein aggregates...
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Source: Drug Week (2011-01-21)
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