Lung Cancer
Hamamatsu University, Department of Pathology Publishes Research in Lung Cancer
Published in Drug Week, January 21st, 2011
2011 JAN 21 -- New research, 'Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma,' is the subject of a report. According to recent research from Hamamatsu, Japan, "The candidate tumor suppressor NORE1A is a nucleocytoplasmic shuttling protein, and although a fraction of the NORE1A in cells is localized to their centrosomes, the role of centrosomal NORE1A has not been elucidated. In this study we investigated the role of NORE1A in the numerical integrity of centrosomes and chromosome stability in lung cancer cells."
"Exposure of p53-deficient H1299 lung cancer...
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Source: Drug Week (2011-01-21)
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