DNA Research
New Dna Research Findings from National Cancer Institute Published
Published in Drug Week, January 21st, 2011
2011 JAN 21 -- Current study results from the report, 'Efficient repair of DNA double-strand breaks in malignant cells with structural instability,' have been published. "Aberrant repair of DNA double-strand breaks (DSBs) is thought to be important in the generation of gross chromosomal rearrangements (GCRs). To examine how DNA DSBs might lead to GCRs, we investigated the repair of a single DNA DSB in a structurally unstable cell line," researchers in the United States report.
"An I-SceI recognition site was introduced into OVCAR-8 cells between a constitutive promoter (EF1alpha) and the Herpes simplex virus thymidine kinase (TK) gene, which confers...
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Source: Drug Week (2011-01-21)
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