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Proteomics

New Proteomics Study Findings Recently Were Reported by Researchers at Shanghai Jiao Tong University, Shanghai Institute of Hypertension

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- New research, 'Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression,' is the subject of a report. According to a study from Shanghai, People's Republic of China, "Profilin-1 has recently been linked to vascular hypertrophy and remodeling. Here, we assessed the hypothesis that angiotensin (Ang) II type I receptor antagonist telmisartan improves vascular hypertrophy by modulation of expression of profilin-1 and angiotensin-converting enzyme 2 (ACE2)."

"Ten-week-old male spontaneously hypertensive rats (SHR) were received oral administration of telmisartan (5 or 10mg/kg; daily) or...

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