Ubiquitins
Scientists at Sam and Ann Barshop Institute for Longevity and Aging Studies Publish New Data on Ubiquitins
Published in Drug Week, January 21st, 2011
2011 JAN 21 -- A new study, 'The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway,' is now available. "After undergoing several rounds of divisions normal human fibroblasts enter a terminally non-dividing state referred to as cellular or replicative senescence. We cloned MORF4 (mortality factor on human chromosome 4), as a cellular senescence inducing gene that caused immortal cells assigned to complementation group B for indefinite division to stop dividing," scientists in the United States report.
"To facilitate analyses of this gene, which is toxic to cells at low levels, we obtained stable...
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Source: Drug Week (2011-01-21)
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