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Pseudomonas aeruginosa

Studies from Tongji Hospital, Department of Infectious Diseases in the Area of Pseudomonas Aeruginosa Published

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- New investigation results, 'Pseudomonas aeruginosa pvdQ gene prevents Caco-2 cells from obstruction of quorum-sensing signal,' are detailed in a study published in Current Microbiology. "Quorum sensing (QS) system plays an important role in bacterial pathopoiesis of incurable Pseudomonas aeruginosa infection, which strongly warrants new strategies for absence of curative treatment to date. Latest investigations show that pvdQ gene of P. aeruginosa can attenuate the pathopoiesis of the bacteria by encoding acylase enzyme and hydrolyze N-(3-oxododecanoyl)-Homoserine Lactone (3O-oxo-C(12)-HSL), the key signal molecule of QS system," researchers...

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