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Cell Proliferation

University of Texas Health Science Center at Houston, Institute of Molecular Medicine for the Prevention of Human Diseases Reports Research in Cell Proliferation

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- Data detailed in 'Role of soluble guanylyl cyclase-cyclic GMP signaling in tumor cell proliferation' have been presented. "Our previous studies demonstrate a differential expression of nitric oxide (NO) signaling components in ES cells and our recent study demonstrated an enhanced differentiation of ES cells into myocardial cells with NO donors and soluble guanylyl cyclase (sGC) activators. Since NO-cGMP pathway exhibits a diverse role in cancer, we were interested in evaluating the role of the NO-receptor sGC and other components of the pathway in regulation of the tumor cell proliferation," researchers in the United States report.

"Our...

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