Central Nervous System Depressants

Research from University of Zurich Has Provided New Data on Central Nervous System Depressants

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- According to recent research from Zurich, Switzerland, "Autoregulation, an important feature of the cerebral circulation, is affected in many diseases. Since genetically modified mice are a fundamental tool in biomedical research, including neuro(bio)logy also in this specie measurements of cerebral autoregulation (CA) are mandatory."

"However, this requires anesthesia that unfortunately significantly impacts cerebral perfusion and consequently might distort CA measurements directly or by altering arterial pCO(2). The latter can be avoided by artificial ventilation but requires several control measurements of blood gases, each consuming at...

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Source: Drug Week (2011-01-21)

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