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Biomembranes

Studies Conducted at R. Brasseur et al on Biomembranes Recently Published

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- "The recent discovery of new potent therapeutic molecules that do not reach the clinic due to poor delivery and low bioavailability has made of delivery a keystone in therapeutic development. Several technologies have been designed to improve cellular uptake of therapeutic molecules, including cell-penetrating peptides (CPPs)," scientists in Montpellier, France report.

"CPPs were discovered 20 years ago based on the potency of several proteins to enter cells. So far numerous CPPs have been described which can be grouped into two major classes, the first requiring chemical linkage with the drug for cellular internalization, the second...

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