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Inorganic Chemicals

Data on Inorganic Chemicals Reported by Researchers at Shandong University, Department of Pharmacology

Published in Drug Week, January 21st, 2011

2011 JAN 21 -- New research, 'TMPDP, a tetramethylpyrazine derivative, protects vascular endothelial cells from oxidation damage by hydrogen peroxide,' is the subject of a report. "A novel ligustrazine derivative, tetramethylpyrazine diphenylmethyl piperazidine (TMPDP), prepared by hybridization and bioisosteric replacement of the molecular structure of TMP, was studied for its protective effects on oxidative damage of human umbilical vein endothelial cells (HUVECs) in response to hydrogen peroxide (H2 O2 ). The antioxidative effect of TMPDP was assessed by the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) test," scientists writing in the journal...

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