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Leukemia

Reports by R.K. Gandhirajan and Co-Researchers Describe Recent Advances in Leukemia

Published in Drug Week, February 4th, 2011

2011 FEB 4 -- Scientists discuss in 'Wnt/ß-catenin/LEF-1 signaling in chronic lymphocytic leukemia (CLL): a target for current and potential therapeutic options' new findings in Leukemia. According to recent research from Cologne, Germany, "There is a growing body of evidence that Wnt signaling, which is already known to play a critical role in various types of cancer, also has a vital function in B cell neoplasias, particularly in chronic lymphocytic leukemia (CLL). It is known that Wnt proteins are overexpressed in primary CLL cells and several physiological inhibitors are partly inactivated in this disease."

"Furthermore, ß-catenin is...

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