Gliomas

Studies in the Area of Gliomas Reported from National Cheng Kung University, Center for Gene Regulation

Published in Drug Week, February 11th, 2011

2011 FEB 11 -- A new study, 'Minocycline inhibits the growth of glioma by inducing autophagy,' is now available. "Minocycline has been shown to alleviate several neurological disorders. Unexpectedly, we found that minocycline had opposite effects on glioma cells: minocycline induced nonapoptotic cell death in glioma cells," scientists in Tainan, Taiwan report.

"The glioma cell death was associated with the presence of autophagic vacuoles in the cytoplasm. Minocycline induced autophagy was confirmed by acridine orange, monodansylcadaverine (MDC) stainings of vesicle formation and the conversion of microtubule-associated proteins light chain 3 (LC3-I) to...

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Source: Drug Week (2011-02-11)

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