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Neuroblastomas

Research from K. Otake and Co-Authors in the Area of Neuroblastomas Published

Published in Drug Week, April 15th, 2011

2011 APR 15 -- "We investigated the associations between hsMAD2 mRNA expression in tumor cells and sensitivity to paclitaxel or patient prognosis in neuroblastoma. Fifty-one formalin-fixed paraffin-embedded tumor samples were manually microdissected to collect tumor cells, and RNA was purified," scientists writing in the journal Pediatric Surgery International report.

"Nineteen clinical samples of advanced neuroblastoma showed appropriate quality of the isolated RNA for real-time reverse transcription-polymerase chain reaction (RT-PCR) analyses. The hsMAD2 expression levels were determined by real-time RT-PCR in 4 neuroblastoma cell lines and 19...

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