Alcohol Oxidoreductases
Study Data from State University of New York Provide New Insights into Alcohol Oxidoreductases
Published in Drug Week, June 3rd, 2011
2011 JUN 3 -- New investigation results, "Inhibition of the M. tuberculosis 3ß-hydroxysteroid dehydrogenase by azasteroids," are detailed in a study published in Bioorganic & Medicinal Chemistry Letters. According to recent research from Stony Brook, United States, "The cholesterol metabolism pathway in Mycobacterium tuberculosis (M. tb) is a potential source of energy as well as secondary metabolite production that is important for survival of M. tb in the host macrophage. Oxidation and isomerization of 3ß-hydroxysterols to 4-en-3-ones is requisite for sterol metabolism and the reaction is catalyzed by 3ß-hydroxysteroid dehydrogenase...
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Source: Drug Week (2011-06-03)
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