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Aromatic Amino Acids

Data on Aromatic Amino Acids Detailed by Researchers at University of California

Published in Drug Week, June 3rd, 2011

2011 JUN 3 -- A report, "Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling," is newly published data in Science Signaling. According to recent research from Los Angeles, United States, "In subtypes and late stages of leukemias driven by the tyrosine kinase fusion protein Bcr-Abl, signaling by the Src family kinases (SFKs) critically contributes to the leukemic phenotype. We performed global tyrosine phosphoprofiling by quantitative mass spectrometry of Bcr-Abl-transformed cells in which the activities of the SFKs were perturbed to build a detailed context-dependent network of cancer signaling."

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