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Paracetamol Therapy

Findings in Paracetamol Therapy Reported from University of London

Published in Drug Week, August 12th, 2011

2011 AUG 12 -- According to the authors of recent research from London, United Kingdom, "Emulsion-solvent evaporation is an established method to fabricate amorphous drug-loaded microparticles. In some cases, however, the encapsulated drug is present in its crystalline form, which can affect drug release and negatively impact on other characteristics of the final product."

"This work aimed to investigate the factors that are responsible for the formation (and inhibition) of drug crystals in modified-release microparticles. Five acidic drugs were encapsulated into Eudragit S or Eudragit L microparticles. Drug crystallinity was observed when indometacin and...

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