Adenocarcinomas

Research Results from National Sun Yat Sen University Update Knowledge of Adenocarcinomas

Published in Drug Week, September 9th, 2011

2011 SEP 9 -- "A series of polyfluorinated bipyridine cisplatins 2-6 were prepared, characterized, and evaluated for their in vitro cytotoxicities against a panel of human cancer cell lines, MCF7 (breast adenocarcinoma), MDA-MB-231 (breast adenocarcinoma) and A549 (lung adenocarcinoma)," researchers in Kaohsiung, Taiwan report.

"The results show that a correlation between the relative order of lipophilicity of complexes 2-4 and their cytotoxicity is established by following the trend: 4> 2> 3. Complex 4, which is the most active compound in the series, was found to be a more effective and selective anticancer agent than cisplatin," wrote T.T. Chang...

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Source: Drug Week (2011-09-09)

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