Melanomas

Studies from University of the Republic Further Understanding of Melanomas

Published in Drug Week, September 16th, 2011

2011 SEP 16 -- According to the authors of recent research from Montevideo, Uruguay, "Study of fluorophore and technetium labeling of poly(amido)-amine (PAMAM) generation 4 (G4) dendrimer and its evaluation as potential molecular imaging agent in both normal and melanoma-bearing mice, are described. Dendrimers were first conjugated with FITC (fluorescein isothiocyanate)."

"Dendrimer-FITC was then incubated with the intermediate [Tc-99m(CO)(3)(H2O)(3)](+) and purified by gel filtration. Biodistribution and scintigraphy images were performed administrating Tc-99m(CO)(3)-dendrimer-FITC to normal mice (NM) or melanoma-bearing mice (MBM). Cryostat tissue...

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Source: Drug Week (2011-09-16)

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