Drug Development
Findings from A. Meena and Co-Authors Broaden Understanding of Drug Development
Published in Drug Week, October 14th, 2011
2011 OCT 14 -- According to the authors of recent research from Uttar Pradesh, India, "Natural coumarinolignoids isolated from the seeds of Cleome viscosa consist of a racemic mixture of cleomiscosins A, B and C. To screen out potential lead, anti-inflammatory activity of the isolated compounds was evaluated through molecular docking and QSAR studies by using reported in vivo activity of Swiss albino mice. Based on docking binding affinity, a possible mechanism of action has been hypothesized which constitute toll-like receptors (TLR-4), cluster of differentiation molecules (CDs), iNOS, COX-2 and STAT-6 proteins."
"It was very interesting to find that the...
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Source: Drug Week (2011-10-14)
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