Published in Drug Week, October 14th, 2011
"Its long-term use can cause neurodegenerative disorders due to its prolonged activation of microglia. The present study proved that the use of epicatechin prior to DOX treatment significantly attenuated not only the increase in TNF-alpha, iNOS and NF-kappa B expressions but also the increase in TNF-alpha and total nitrite levels in brain tissue when compared with rats treated with DOX-only," wrote R.H. Mohamed...
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