Drug Delivery Systems
New Drug Delivery Systems Data Have Been Reported by Scientists at Medical College of Wisconsin
Published in Drug Week, October 28th, 2011
2011 OCT 28 -- Research findings, "Permeabilization of the mitochondrial outer membrane by Bax/truncated Bid (tBid) proteins as sensitized by cardiolipin hydroperoxide translocation: mechanistic implications for the intrinsic pathway of oxidative apoptosis," are discussed in a new report. According to the authors of a study from Milwaukee, Wisconsin, "Cytochrome c (cyt c) release upon oxidation of cardiolipin (CL) in the mitochondrial inner membrane (IM) under oxidative stress occurs early in the intrinsic apoptotic pathway. We postulated that CL oxidation mobilizes not only cyt c but also CL itself in the form of hydroperoxide (CLOOH) species."
"Relatively...
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Source: Drug Week (2011-10-28)
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