Biochemistry

Data on Biochemistry Detailed by Researchers at University of Michigan

Published in Drug Week, October 28th, 2011

2011 OCT 28 -- "ATP1B4 genes represent a rare instance of the orthologous gene co-option that radically changed functions of encoded BetaM proteins during vertebrate evolution. In lower vertebrates, this protein is a beta-subunit of Na,K-ATPase located in the cell membrane," scientists writing in the journal Biochemical and Biophysical Research Communications report.

"In placental mammals, BetaM completely lost its ancestral role and through acquisition of two extended Glu-rich clusters into the N-terminal domain gained entirely new properties as a muscle-specific protein of the inner nuclear membrane possessing the ability to regulate gene...

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Source: Drug Week (2011-10-28)

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