Vaccines
Study Data from Harvard University Provide New Insights into Vaccines
Published in Drug Week, November 4th, 2011
2011 NOV 4 -- "We previously engineered a macroporous, polymer-based vaccine that initially produces GM-CSF gradients to recruit local dendritic cells and subsequently presents CpG oligonucleotides, and tumor lysate to cell infiltrates to induce immune cell activation and immunity against tumor cells in peripheral tumor models. Here, we demonstrate that this system eradicates established intracranial glioma following implantation into brain tissue, whereas implantation in resection cavities obviates vaccine efficacy," researchers in Cambridge, Massachusetts report.
"Rats bearing seven-day old, intracranial glioma tumors were treated with PLC vaccines...
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Source: Drug Week (2011-11-04)
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