Alcoholism
Data on Alcoholism Discussed by K.N. Spreckelmeyer and Colleagues
Published in Drug Week, November 25th, 2011
2011 NOV 25 -- "Preclinical data implicate the reinforcing effects of alcohol to be mediated by interaction between the opioid and dopamine systems of the brain. Specifically, alcohol-induced release of beta-endorphins stimulates mu-opioid receptors (MORs), which is believed to cause dopamine release in the brain reward system," scientists writing in the journal Biological Psychiatry report.
"Individual differences in opioid or dopamine neurotransmission have been suggested to be responsible for enhanced liability to abuse alcohol. In the present study, a single dose of the MOR agonist remifentanil was administered in detoxified alcohol-dependent...
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Source: Drug Week (2011-11-25)
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