Cell Surface Extensions

New Data from University of Okayama Illuminate Research in Cell Surface Extensions

Published in Drug Week, November 25th, 2011

2011 NOV 25 -- "Almost all mammalian cells carry one primary cilium that functions as a biosensor for chemical and mechanical stimuli. Genetic damages that compromise cilia formation or function cause a spectrum of disorders referred to as ciliapathies," investigators in Okayama, Japan report.

"Recent studies have demonstrated that some pharmacological agents and extracellular environmental changes can alter primary cilium length. Renal injury is a well-known example of an environmental insult that triggers cilia length modification. Lithium treatment causes primary cilia to extend in several cell types including neuronal cells; this phenomenon is likely...

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Source: Drug Week (2011-11-25)

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