Catecholamine Receptors
Research on Catecholamine Receptors Discussed by Scientists at Scripps Research Institute
Published in Drug Week, November 25th, 2011
2011 NOV 25 -- "Mechanism of G protein-coupled receptor (GPCR) activation and their modulation by functionally distinct ligands remains elusive. Using the technique of amide hydrogen/deuterium exchange coupled with mass spectrometry, we examined the ligand-induced changes in conformational states and stability within the beta-2-adrenergic receptor (beta(2)AR)," scientists in Jupiter, Florida report.
"Differential HDX reveals ligand-specific alterations in the energy landscape of the receptor's conformational ensemble. The inverse agonists timolol and carazolol were found to be most stabilizing even compared with the antagonist alprenolol, notably in...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Drug Week
Source: Drug Week (2011-11-25)
More Articles from Drug Week
- Psychiatry
Data from University of Geneva Advance Knowledge in Psychiatry - Ampicillins
Data on Ampicillins Discussed by H. Akhter and Colleagues - Apoptosis
Data on Apoptosis Reported by Researchers at Sungkyunkwan University - Cancer Therapy
Data on Cancer Therapy Published by Researchers at Southern Medical University - Drug Development
Data on Drug Development Discussed by A.D. Ruikar and Colleagues - Nanoparticles
Data on Nanoparticles Discussed by S. Vrignaud and Colleagues - More from this issue of Drug Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
