Glycyrrhetinic Acid
Research Reports from A.E. Chavez-Pina and Co-Authors Provide New Insights into Glycyrrhetinic Acid
Published in Drug Week, January 6th, 2012
2012 JAN 6 -- According to the authors of recent research from Mexico City, Mexico, "Carbenoxolone, a semi-synthetic triterpenoid, exhibits gastroprotective activity related to the participation of nitric oxide (NO); however, the complete NO/©GMP/K-ATP channels pathway for carbenoxolone is unknown. Therefore the aim of this study was to examine the NO/©GMP/K-ATP channels pathway as the gastroprotective mechanism of carbenoxolone in the ethanol-induced gastric injury model in the rat."
"Oral administration of carbenoxolone (30 mg/kg, p.o.) exhibited gastroprotective effect against ethanol-induced gastric injury in rats. Pretreatment with...
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Source: Drug Week (2012-01-06)
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