Anti-Infectives
Study Results from Saurashtra University in the Area of Anti-Infectives Published
Published in Drug Week, January 20th, 2012
2012 JAN 20 -- Investigators discuss in "Synthesis and biological evaluation of some novel N-aryl-1,4-dihydropyridines as potential antitubercular agents" new findings in Anti-Infectives. According to the authors of a study from Gujarat, India, "1,4-Dihydropyridines are the emerging class of antitubercular agent. Recently, studies have revealed that 1,4-dihydropyridine-3,5-dicarbamoyl derivatives with lipophilic groups have demonstrated excellent antitubercular activity."
"We have synthesized new N-aryl-1,4-dihydropyridines bearing carbethoxy and acetyl group at C-3 and C-5 of the DHP ring. In addition, 1H-pyrazole ring is substituted at C-4 position. The...
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Source: Drug Week (2012-01-20)
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