Diabetes
Research on Diabetes Detailed by Scientists at Medical Center
Published in Drug Week, February 10th, 2012
2012 FEB 10 -- Research findings, "Enhanced angiotensin II-mediated central sympathoexcitation in streptozotocin-induced diabetes: role of superoxide anion," are discussed in a new report. "Studies have shown that the superoxide mechanism is involved in angiotensin II (ANG II) signaling in the central nervous system. We hypothesized that ANG II activates sympathetic outflow by stimulation of superoxide anion in the paraventricular nucleus (PVN) of streptozotocin (STZ)-induced diabetic rats," investigators in Omaha, Nebraska report.
"In a-chloralose-and urethane-anesthetized rats, microinjection of ANG II into the PVN (50, 100, and 200 pmol) produced...
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Source: Drug Week (2012-02-10)
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