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Phosphoric Diester Hydrolases

New Findings Reported from Pusan National University Describe Advances in Phosphoric Diester Hydrolases

Published in Drug Week, March 16th, 2012

2012 MAR 16 -- Investigators publish new data in the report "Intermolecular association between caspase-mediated cleavage fragments of phospholipase D1 protects against apoptosis. 'Phospholipase D plays an anti-apoptotic role but little is known about dynamics of phospholipase D turnover during apoptosis. We have recently identified phospholipase D1 as a new substrate of caspases which generates the N-terminal and C-terminal fragment of phospholipase D1," scientists in Busan, South Korea report.

"In the present study, we tried to investigate whether association of the caspase cleavage fragments may be involved in regulation of apoptosis. Ectopically...

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