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National Tumor Institute, Milan

Reports advance knowledge in oncology research

Published in Elder Law Weekly, April 13th, 2005

Reports from Italy and the United States highlight recent research on oncology.

Study 1: Cells normally protected from apoptosis are vulnerable to Fhit gene induction.

"The expression of the tumor suppressor protein fragile histidine triad (Fhit) is often impaired in many human cancers and its restoration in Fhit-negative cancer cell lines suppresses tumorigenicity and induces apoptosis. Although the proapoptotic function of Fhit is well documented, little is known about its precise mechanism of action and further studies are needed in order to elucidate the putative therapeutic properties of this protein," investigators in Italy report.

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