Elder Law Weekly
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INSERM U433, Lyon
Activated T lymphocytes studied, blood-cerebrospinal fluid barrier clarified
October 26th, 2005
A study from France has documented impairment of blood-cerebrospinal fluid (CSF) barrier properties by retrovirus-activated T lymphocytes. "The choroid plexus epithelium forms the interface between the blood and the CSF. In conjunction with the tight junctions restricting the paracellular pathway, polarized specific transport systems in the choroidal epithelium allow a fine regulation of CSF-borne biologically active mediators," wrote S.T. Khuth and colleagues, INSERM. "The highly vascularized stroma delimited by the choroidal epithelium can be a reservoir for retrovirus-infected or activated immune cells. In this work, new insight in the implication...
Source: Elder Law Weekly (2005-10-26)
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