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Cell Research

Data on cell research detailed by researchers at Harvard University, Department of Genetics

Published in Elder Law Weekly, December 29th, 2010

2010 DEC 29 -- A report, 'FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging,' is newly published data in Cell. According to a study from the United States, "The progressive loss of muscle strength during aging is a common degenerative event of unclear pathogenesis. Although muscle functional decline precedes age-related changes in other tissues, its contribution to systemic aging is unknown."

"Here, we show that muscle aging is characterized in Drosophila by the progressive accumulation of protein aggregates that associate with impaired muscle function. The transcription factor FOXO and its target 4E-BP...

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