Albert Einstein College of Medicine
Efficacy of taxol affected by mitogen-activated protein kinase inhibitor CI-1040
Published in FDA Law Weekly, May 26th, 2005
"Taxol may contribute to intrinsic chemoresistance by activating the MEK/ extracellular signal-regulated kinase (ERK) cytoprotective pathway in human cancer cell lines and tumors. We have previously shown additivity between Taxol and the MEK inhibitor, U0126 in human cancer cell lines. Here, the combination of Taxol with an orally bioavailable MEK inhibitor, CI-1040, was evaluated in human lung tumors heterotransplanted into nude mice," scientists in the United States reported.
"Unlike xenograft models...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of FDA Law Weekly
Source: FDA Law Weekly (2005-05-26)
More Articles from FDA Law Weekly
- AMTSystems
Identification device for surgical safety introduced in healthcare industry - Adeza
Test assesses risk of preterm birth - Adventrx Pharmaceuticals, Inc.
U.S. FDA grants clearance for CoFactor phase III trial in colorectal cancer - Alcon, Inc.
New intraocular lens launched - BioAlliance Pharma
U.S. FDA grants orphan drug designation for doxorubicin Transdrug - Cellegy Pharmaceuticals, Inc.
Pharmaceutical firm responds to U.S. FDA inquiries about Cellegesic - More from this issue of FDA Law Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
