Published in FDA Law Weekly, May 26th, 2005
"The core of the star polymer is polyamidoamine (PAMAM) dendrimer, the inner block in the arm is lipophilic poly(epsilon-caprolactone) (PCL), and the outer block in the arm is hydrophilic poly(ethylene glycol) (PEG)," scientists in Massachusetts explained. "The star-PCL polymer was synthesized first by ring-opening polymerization of E-caprolactone with a PAMAM-OH dendrimer as initiator."
"The PEG polymer was then attached to the PCL terminus by an ester-forming reaction," added F. Wang and coauthors working at EIC Laboratories in Norwood....
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