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U.S. Food & Drug Administration

Data mining methods on the Vaccine Adverse Event Reporting System database compared

Published in FDA Law Weekly, November 17th, 2005

Investigators compare data mining methods on the Vaccine Adverse Event Reporting System (VAERS) database in a recent issue of Pharmacoepidemiology and Drug Safety.

According to recent research from the United States, "Data mining may enhance traditional surveillance of vaccine adverse events by identifying events that are reported more commonly after administering one vaccine than other vaccines. Data mining methods find signals as the proportion of times a condition or group of conditions is reported soon after the administration of a vaccine; thus it is a relative proportion compared across vaccines, and not an absolute rate for the condition."

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