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FDA Law Weekly

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Cancer Therapy



Recent studies from University of Heidelberg, Department of Pathophysiology add new data to cancer therapy



March 15th, 2007

New investigation results, "Low postabsorptive net protein degradation in male cancer patients: lack of sensitivity to regulatory amino acids," are detailed in a study published in Oncology Reports. According to recent research published in the journal Oncology Reports, "Autophagic (lysosomal) and proteasomic protein degradation are important regulatory mechanisms in the homeostasis of muscle mass, that may be profoundly disturbed in cancer and other wasting syndromes. Due to the inhibiting effect of amino acids and insulin, net proteolysis is restricted to the fasted state, and in autophagy certain amino acids have been identified as 'regulatory' in the rat, including leucine,...


Source: FDA Law Weekly (2007-03-15)

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