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FDA Law Weekly

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Cancer Vaccines



Scientists at Uppsala University discuss research in cancer vaccines



March 15th, 2007

New investigation results, "Modifications increasing the efficacy of recombinant vaccines; marked increase in antibody titers with moderately repetitive variants of a therapeutic allergy vaccine," are detailed in a study published in Vaccine. According to a study from Uppsala, Sweden, "Development of vaccines targeting important self-molecules like tumor antigens, IgE, cytokines or other regulatory molecules, brings about challenges that are not met in classical vaccine development. Tolerance inducing mechanisms reduce the levels of therapeutic antibodies in the vaccinated subject, and anti-self antibody titers are frequently more than 50-fold lower than the anti-non-self response to the...


Source: FDA Law Weekly (2007-03-15)

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