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Toxicology

Research reports from National Institute of Health Science provide new insights into toxicology

Published in FDA Law Weekly, March 22nd, 2007

Research findings, "ELISA method for monitoring human serum IgE specific for Cry1Ab introduced into genetically modified corn," are discussed in a new report. According to recent research from Setagaya, Japan, "Enzyme-linked immunosorbent assay (ELISA) is the most convenient method of monitoring the occurrence of IgE antibodies specific for novel proteins in genetically modified (GM) foods. The levels of IgE specific for a recombinant protein, Cry1Ab, were determined using an ELISA method."

"A soluble form of the Cry1Ab protein purified from pCold1 vector-transformed Escherichia coli pTf16/BL21 was used as the ELISA coating antigen, and 1M NaCl was used as the...

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