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DOE/Argonne National Laboratory

Argonne researchers develop method that aims to stabilize antibodies

Published in FDA Law Weekly, September 24th, 2009

Researchers at the U.S. Department of Energy's Argonne National Laboratory have developed a systematic method to improve the stability of antibodies. The technique could lead to better biosensors, disease therapeutics and diagnostic reagents and non-laboratory applications, including environmental remediation.

Antibodies are proteins produced by humans and animals to defend against infections; they are also used to diagnose and treat some diseases and detect toxins and pathogens. "The primary issues with antibodies is that they are fragile and short-lived outside of cooler temperature-controlled environments, making their usefulness usually limited to laboratory...

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